Colesevelam is a bile acid sequestrant. Colesevelam is a nonabsorbed bile acid sequestrant that is used a therapy of hyperlipidemia and for the pruritus of chronic liver disease and biliary obstruction.
Colesevelam is a bile acid sequestrant administered orally.
Colesevelam. Bile acid sequestrants are ion exchange polymers that bind bile acids in the gut. It is used to lower cholesterol. Menurunkan kolesterol jahat dalam darah yang juga disebut kolesterol ldl low density lipoprotein menurunkan ldl dapat mengurangi risiko arteri yang mengeras yang dapat menyebabkan serangan jantung stroke.
Uses of colesevelam tablets. Menurunkan kolesterol bantu mengurangi risiko penyakit jantung dan membantu mencegah stroke dan serangan jantung. Colesevelam may be prescribed on its own to treat high cholesterol or you may also be given other lipid lowering medicines to take alongside it.
Colesevelam adalah obat penurun kolesterol. Last updated on oct 23 2020. Colesevelam hcl is a hydrophilic water insoluble polymer not hydrolyzed by digestive enzymes and is not absorbed.
Colesevelam has not been associated with clinically apparent liver injury. Before taking colesevelam some medicines are not suitable for people with certain conditions and sometimes a medicine may only be used if extra care is taken. Colesevelam is sometimes used together with statin cholesterol medications such as atorvastatin lovastatin simvastatin crestor lipitor pravachol zocor and others.
Distribution is limited to the gastrointestinal tract. It was developed by geltex pharmaceuticals and later acquired by genzyme. Colesevelam is a bile acid sequestrant.
It is marketed in the us by daiichi sankyo under the brand name welchol and elsewhere by genzyme as cholestagel. Colesevelam is used to treat high cholesterol in adults and children at least 10 years old. Colesevelam tablets koh le sev a lam brand name.
In canada it is marketed by valeant as lodalis. 1 2 3 menurunkan kolesterol tinggi hiperkolesterolemia pada orang dewasa dan anak anak minimal 10 tahun. Colesevelam is used with exercise and diet changes restriction of cholesterol and fat intake to reduce the amount of cholesterol and certain fatty substances in the blood.
It works by binding bile acids in the intestine. It is used to lower blood sugar in patients with high blood sugar diabetes. Not metabolized systemically and does not interfere with systemic drug metabolizing enzymes eg cyp450 elimination.
Colesevelam memiliki beberapa kegunaan terutama untuk. Obati ini digunakan bersamaan dengan pola makan yang baik dan olahraga untuk menurunkan kolesterol pada orang yang memiliki tingkat kolesterol tinggi. Ion exchange polymers are insoluble organic polymers which trap ions and in doing so release others 23 there are four main types.