The nahco 3 wash serves to neutralize the acid and to remove water soluble polar compounds. Nacl is not basic.
What is the purpose of the saturated sodium chloride wash.
Is nacl polar protic. The most common polar protic solvents are the water and alcohols. Protic vs aprotic solvents. Polar protic and polar aprotic.
While in any polar aprotic solvent the order of nucleophilicity is ce f ce cl ce br ce i. Awesome lg sn1. Protic solvents solvate anions negatively charged solutes strongly via hydrogen bonding.
A reaction work up for an aqueous reaction mixture calls for extraction first with diethyl ether and then a wash with saturated aqueous sodium chloride. For example when nacl is dissolve in water the sodium ion is solvated through a dipole dipole interaction by the oxygen and the cl. No base sn1 sn2.
Solvents used in organic chemistry are characterized by their physical characteristics. Tbuoh is a polar protic solvent sn1. For example when sodium chloride is added to a solution of dmso.
Polar aprotic solvents favor s n 2 while polar protic solvents favor s n 1. It s tertiary at the leaving group sn1. Why does the finkelstein reaction use acetone in spite of the fact that it is a polar aprotic solvent.
Because non polar solvents tend to be aprotic the focus is upon polar solvents and their structures. Among the most important are whether the solvents are polar or non polar and whether they are protic or aprotic. Solvents with a dielectric constant more accurately relative static permittivity greater than 15 i e.
Polar or polarizable can be further divided into protic and aprotic. All of the factors point to an sn1 reaction therefore i feel comfortable saying it is an sn1 reaction. Otf is a dynamite leaving group.
The reason for this is that polar aprotic solvents tend to interact with the counterion of the nucleophile leaving the nucleophile naked thus more reactive. Wouldn t using a polar protic solvent be better since it would make ce i the strongest nucleophile of the group. Water is a protic solvent.